Allergy, Epidemiology, Causes And Pathogenesis, Immunology

An allergy is an abnormal reaction to an ordinarily harmless substance or substances. These sensitizing substances, called allergens, may be inhaled, swallowed, or come into contact with the skin. When an allergen is absorbed into the body, it triggers white blood cells to produce IgE antibodies. These antibodies attach themselves to mast cells causing a release of potent chemical mediators such as histamine; this causes typical allergic symptoms.


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